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TB-500 is a synthetic peptide derived from a functional segment of thymosin beta-4 and is composed of 43 amino acids. It is examined for its involvement in tissue-remodeling processes, cellular migration, and actin-related regulation. In vitro studies investigate TB-500’s influence on angiogenic signaling, modulation of inflammatory pathways, and mechanisms associated with wound-model repair. The peptide is of particular interest in epithelial and connective-tissue research due to its effects on cytoskeletal organization and cell-motility dynamics.