CAGRILITIDE KIT

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Cagrilintide is a synthetic peptide analogue that functions as an amylin-receptor agonist. It is a modified form of the human amylin peptide, engineered to enhance molecular stability and receptor selectivity. Amylin itself is a 37–amino acid peptide co-secreted with insulin by pancreatic β-cells, and its analogues are used to investigate pathways related to energy balance, satiety signaling, and glycemic-regulation mechanisms in preclinical research models.

Cagrilintide contains targeted amino-acid substitutions that increase resistance to enzymatic breakdown, yielding improved structural persistence compared to the native peptide. Research efforts focus on its interaction with the amylin-receptor complex—comprising the calcitonin receptor and associated receptor activity-modifying proteins (RAMPs). Ongoing studies examine its pharmacological profile, receptor-binding characteristics, and its utility in metabolic-pathway research.